Hi Rob,
Try getting rid of both ezcomfil and ezcurfil in addition to ADSPROF. If you only remove ADSPROF, it will attempt to recreate itself based on the information in the other 2 files.
The reason for the 'Error 1305 - unknown DOS error accessing eztasks file' is because another process (such as Accpac Plus) is locking that file. Try finding the eztasks.ld4 file (in the directory you are entering) and rename it; if you are unable to it means that you either don't have Permissions to write to the file (which you require) or the file has been locked and inaccessible.
My guess is that you delete ADSPROF and enter the path, this is the correct step, but another process is getting in the way.
1) Do you use Accpac Plus?
2) Do you have any Lanpaks for Accpac installed?
If the answer to 1) is 'Yes' and 2) is 'No', and you are entering \ASP as the location of eztasks, this is the reason for your error. Accpac Plus locks the eztasks file to the exclusion of any other process (including itself!) with any Lanpaks installed.
Try entering \softrak\system as the paths, instead of \asp.